Document Detail

Acute gastroenteritis: from guidelines to real life.
MedLine Citation:
PMID:  21694853     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Acute gastroenteritis is a very common disease. It causes significant mortality in developing countries and significant economic burden to developed countries. Viruses are responsible for approximately 70% of episodes of acute gastroenteritis in children and rotavirus is one of the best studied of these viruses. Oral rehydration therapy is as effective as intravenous therapy in treating mild to moderate dehydration in acute gastroenteritis and is strongly recommended as the first line therapy. However, the oral rehydration solution is described as an underused simple solution. Vomiting is one of the main reasons to explain the underuse of oral rehydration therapy. Antiemetics are not routinely recommended in treating acute gastroenteritis, though they are still commonly prescribed. Ondansetron is one of the best studied antiemetics and its role in enhancing the compliance of oral rehydration therapy and decreasing the rate of hospitalization has been proved recently. The guidelines regarding the recommendation on antiemetics have been changed according to the evidence of these recent studies.
Chung M Chow; Alexander Kc Leung; Kam L Hon
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Publication Detail:
Type:  Journal Article     Date:  2010-07-15
Journal Detail:
Title:  Clinical and experimental gastroenterology     Volume:  3     ISSN:  1178-7023     ISO Abbreviation:  Clin Exp Gastroenterol     Publication Date:  2010  
Date Detail:
Created Date:  2011-06-22     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101532800     Medline TA:  Clin Exp Gastroenterol     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  97-112     Citation Subset:  -    
Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, PR China;
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