Document Detail


Acute funisitis is associated with distinct changes in fetal hematologic profile.
MedLine Citation:
PMID:  24863633     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: Acute funisitis is a histologic hallmark of the fetal inflammatory response syndrome. This study was conducted to examine the hematologic profiles of preterm newborns with funisitis. Methods: The hematologic profiles of umbilical cord blood obtained at birth were compared according to the presence or absence of acute funisitis in 197 preterm neonates (gestational age before 34 weeks) born to mothers with preterm labor with intact membranes or premature rupture of membranes. Results: 1) Funisitis was identified in 22.3% (44/197) of patients; 2) Neonates with funisitis had higher median leukocyte, neutrophil, monocyte counts (p<0.005 for each), higher rate of neutrophilia (p<0.05), higher proportion of neutrophils among leukocytes, and lower proportion of lymphocytes among leukocytes than those without funisitis (p<0.01 for each); 3) Newborns with funisitis had a significantly lower median RBC count, hemoglobin concentration, and hematocrit than those without funisitis (p<0.05 for each); 4) There was no significant difference in the median lymphocyte, eosinophil, basophil, NRBC, and platelet counts between the two groups (p>0.1 for each). Conclusions: The hematologic profiles of preterm newborns with funisitis are characterized by increased total white blood cell, neutrophil, and monocyte counts and decreased RBC count and hemoglobin concentration.
Authors:
Eun Na Kim; Chong Jai Kim; Jeong Woo Park; Bo Hyun Yoon
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-5-27
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2014 May 
Date Detail:
Created Date:  2014-5-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-19     Citation Subset:  -    
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