Document Detail


Acute fatty liver of pregnancy: a report of two cases.
MedLine Citation:
PMID:  12540067     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute fatty liver of pregnancy is an uncommon, potentially fatal disorder. Between 1998 and 2000, two patients with acute fatty liver of pregnancy presented at the Christian Medical College Hospital, Vellore. Both patients were in the thirty-sixth week of pregnancy. jaundice and encephalopathy were the predominant symptoms. Both the mothers died after they delivered a stillborn Infant each. The maternal deaths were due to multiorgan failure and/or postpartum haemorrhage and sepsis. The route of delivery was vaginal in both the patients. Extrahepatic and metabolic complications in both cases Included renal failure, sepsis, hypoglycaemia, disseminated intravascular coagulation and gastrointestinal bleeding. Liver biopsy done in both patients was consistent with the diagnosis of acute fatty liver of pregnancy. To the best of our knowledge, this is the first report from India on acute fatty liver of pregnancy.
Authors:
G Loganathan; C E Eapen; Rachel G Chandy; Padmini Jasper; Matthews Mathai; Lakshmi Seshadri; Banumathi Ramakrishna; Atanu Kumar Jana; George John; George M Chandy
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The National medical journal of India     Volume:  15     ISSN:  0970-258X     ISO Abbreviation:  Natl Med J India     Publication Date:    2002 Nov-Dec
Date Detail:
Created Date:  2003-01-23     Completed Date:  2003-03-04     Revised Date:  2009-07-30    
Medline Journal Info:
Nlm Unique ID:  8809315     Medline TA:  Natl Med J India     Country:  India    
Other Details:
Languages:  eng     Pagination:  336-8     Citation Subset:  IM    
Affiliation:
Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore 632004, Tamil Nadu, India
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adolescent
Adult
Diagnosis, Differential
Fatal Outcome
Fatty Liver / diagnosis*
Female
Humans
Pregnancy
Pregnancy Complications / diagnosis*

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