| Acute fatty liver of pregnancy complicated with disseminated intravascular coagulation and haemorrhage: a case report. | |
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MedLine Citation:
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PMID: 15875633 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute fatty liver of pregnancy (AFLP) is a rare disorder of unknown aetiology that is diagnosed typically in the third trimester or early postpartum period. The incidence is estimated to be 1/6692-1/13,328. The obstetric team must have a high index of suspicion of this pathology, particularly in the presence of clinical and laboratory findings, such as nausea, vomiting, jaundice, increased serum transaminase levels, increased prothrombin time and hypoglycaemia. Early diagnosis followed by prompt delivery and supportive care provides significantly improved maternal and perinatal outcome. Delay in diagnosis of this obstetric emergency may lead to rapid progression to hepatic failure, disseminated intravascular coagulation (DIC), haemorrhage, encephalopathy, multiple organ failure and finally death. The case of a 34-year-old woman, gravida 3, para 2, with AFLP complicated with DIC is presented herein with a review of literature and discussion of its origin. |
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Authors:
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G Yücesoy; S O Ozkan; H Bodur; Y Cakiroğlu; E Calişkan; S Ozeren |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: International journal of clinical practice. Supplement Volume: - ISSN: 1368-504X ISO Abbreviation: Int J Clin Pract Suppl Publication Date: 2005 Apr |
Date Detail:
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Created Date: 2005-05-06 Completed Date: 2005-07-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9712380 Medline TA: Int J Clin Pract Suppl Country: England |
Other Details:
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Languages: eng Pagination: 82-4 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Kocaeli, School of Medicine, Kocaeli, Turkey. gulserene@superonline.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Disseminated Intravascular Coagulation / etiology* Fatty Liver / complications* Female Humans Postpartum Hemorrhage / etiology* Pregnancy Pregnancy Complications* |
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