| Acute fatty liver in pregnancy. | |
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MedLine Citation:
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PMID: 12572711 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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When confronted with liver abnormalities during the third trimester of pregnancy, one should consider acute fatty liver of pregnancy. The differential diagnosis with (pre-)eclampsia and HELLP syndrome is sometimes difficult. In these cases a liver biopsy is helpful though rarely performed during pregnancy. After delivery of the child the liver test abnormalities will ultimately disappear. Recent publications reveal that a dysfunction in the beta-oxidation of mitochondrial fatty acids may contribute to the aetiology of this rare disorder. We describe a case of acute fatty liver in pregnancy, with liver dysfunction (decreased albumin, prolonged prothrombin time) slowly returning to normal after delivery. Testing for disorders in beta-oxidation of mitochondrial fatty acids did not reveal abnormalities in mother or child. |
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Authors:
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A C I T L Tan; J H J M van Krieken; W H M Peters; E A P Steegers |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Netherlands journal of medicine Volume: 60 ISSN: 0300-2977 ISO Abbreviation: Neth J Med Publication Date: 2002 Oct |
Date Detail:
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Created Date: 2003-02-07 Completed Date: 2003-04-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0356133 Medline TA: Neth J Med Country: Netherlands |
Other Details:
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Languages: eng Pagination: 370-3 Citation Subset: IM |
Affiliation:
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Department of Gastroenterology, University Medical Centre St Radboud, Nijmegen, The Netherlands. a.tan@hccnet.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Diagnosis, Differential Fatty Liver / diagnosis* Female HELLP Syndrome / diagnosis Humans Pre-Eclampsia / diagnosis Pregnancy Pregnancy Complications / diagnosis* |
| Comments/Corrections | |
Comment In:
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Neth J Med. 2002 Oct;60(9):340-2
[PMID:
12572704
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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