| Acute exacerbations of obstructive lung disease. What to do when immediate care is crucial. | |
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MedLine Citation:
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PMID: 7911236 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Obstructive lung disease is a major cause of morbidity and mortality in the United States, and the mortality rate is rising. Successful treatment of acute exacerbations begins with appropriate assessment and intervention. Supplemental oxygen is appropriate for all patients with hypoxemia, and mechanical ventilation should be considered in those with clouded consciousness, profound acidosis, or severe hypoxemia. Inhaled beta 2 agonists are the first line of therapy in acute exacerbations. Anticholinergics, methylxanthines, and corticosteroids may also be useful. Alternative therapies (eg, magnesium, glucagon, calcium channel blockers, clonidine, helium) are receiving increased attention and are undergoing investigation. |
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Authors:
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R E Fromm; J Varon |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Postgraduate medicine Volume: 95 ISSN: 0032-5481 ISO Abbreviation: Postgrad Med Publication Date: 1994 Jun |
Date Detail:
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Created Date: 1994-07-06 Completed Date: 1994-07-06 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0401147 Medline TA: Postgrad Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 101-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Emergency Services, Methodist Hospital, Houston. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Administration, Inhalation Administration, Oral Adrenal Cortex Hormones / therapeutic use Adrenergic beta-Agonists / therapeutic use Adrenergic beta-Antagonists / therapeutic use Aminophylline / therapeutic use Anti-Bacterial Agents / therapeutic use Combined Modality Therapy Drug Therapy, Combination Fluid Therapy Humans Infusions, Intravenous Injections, Subcutaneous Lung Diseases, Obstructive / diagnosis, drug therapy*, mortality, physiopathology Oxygen Inhalation Therapy Respiration, Artificial United States / epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Adrenergic beta-Agonists; 0/Adrenergic beta-Antagonists; 0/Anti-Bacterial Agents; 317-34-0/Aminophylline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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