| Acute endovascular recanalization therapy in wake-up stroke. | |
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MedLine Citation:
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PMID: 21078516 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND AND PURPOSE: Up to 15-25% of patients with ischemic stroke wake up with their deficits. Because of the uncertainty about the time of onset, these patients are generally not offered thrombolytic therapy. Some of these wake-up stroke patients may be eligible for acute endovascular stroke therapy based on hyperacute CT or MR imaging independent of the time window. REPORT: We report two patients with acute ischemic stroke whose symptoms were present upon awakening and who were successfully treated with endovascular interventions. RESULTS: The first patient was discharged with complete neurological recovery on second day after endovascular intervention. The second patient went home on fifth day with a mild left facial paresis and left arm drift. Both these patients did not have any neurological deficit on 18-month follow up. CONCLUSIONS: Some patients who present with stroke on awakening may be candidates for thrombolytic therapy or recanalization techniques irrespective of mode of therapy (intravenous, intravenous+intra-arterial or intra-arterial tPA alone). Further randomized, controlled studies are warranted to safely identify those candidates who would benefit from thrombolysis and endovascular interventions in ischemic wake-up strokes. |
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Authors:
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Abraham Kuruvilla; Gregory M Norris; Andrew R Xavier |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 300 ISSN: 1878-5883 ISO Abbreviation: J. Neurol. Sci. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 148-50 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier B.V. All rights reserved. |
Affiliation:
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WSU/DMC Comprehensive Stroke Program, Department of Neurology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI 48201, USA. akuruvilla@doctor4u.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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