Document Detail

Acute effects of walking on inflammatory and cardiovascular risk in sedentary post-menopausal women.
MedLine Citation:
PMID:  17943596     Owner:  NLM     Status:  MEDLINE    
Biochemical markers of inflammation are emerging as new predictors of risk of cardiovascular disease (CVD) and may alter acutely with exercise. Few studies have been conducted on the effects of walking on these markers or whether different walking intensities elicit varied effects. As there is growing interest in modifiable lifestyle factors such as walking to reduce CVD risk, these inflammatory responses warrant investigation. The aim of this study was to compare the effects of walking at 50% versus 70% of predicted maximal heart rate on C-reactive protein (CRP), plasma fibrinogen, and triglycerides in sedentary post-menopausal women. Twelve post-menopausal women (mean age 58 years, s +/-6; stature 1.62 m, s+/-0.06; body mass 66.8 kg, s +/-6.2) completed two 30-min treadmill walks in a randomized cross-over design. Fasted blood samples were taken (for the determination of plasma fibrinogen, CRP, and lipids) before, immediately after, and 1 and 24 h after exercise. Triglyceride concentrations decreased from pre-exercise to 24 h post exercise at both walking intensities (time x group interaction, P < 0.05). No significant effects were observed for plasma fibrinogen, CRP, total cholesterol, low-density or high-density lipoprotein cholesterol (time x group interaction, P > 0.05). The results of this study suggest that fasting plasma triglycerides are decreased on the morning after 30 min of brisk walking at either 50% or 70% of maximal heart rate (moderate and vigorous intensity).
Jillian Davis; Marie Murphy; Tom Trinick; Ellie Duly; Alan Nevill; Gareth Davison
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of sports sciences     Volume:  26     ISSN:  0264-0414     ISO Abbreviation:  J Sports Sci     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-22     Completed Date:  2008-03-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405364     Medline TA:  J Sports Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  303-9     Citation Subset:  IM    
Sport and Exercise Science Research Institute, University of Ulster, Jordanstown, UK.
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MeSH Terms
C-Reactive Protein / immunology,  metabolism
Cardiovascular Diseases / etiology*
Great Britain
Inflammation / physiopathology*
Middle Aged
Postmenopause / immunology*
Triglycerides / analysis
Walking / physiology*
Reg. No./Substance:
0/Triglycerides; 9001-32-5/Fibrinogen; 9007-41-4/C-Reactive Protein

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