Document Detail

Acute effects of peritoneovenous shunt (Le Veen) on the hemodynamics and gas exchange in patients with hepatic intractable ascites.
MedLine Citation:
PMID:  3225174     Owner:  NLM     Status:  MEDLINE    
The acute effects of the peritoneovenous shunt (LeVeen) on hemodynamics and pulmonary gas exchange in 6 consecutive patients with intractable ascites and cirrhosis were evaluated. After opening the peritoneovenous shunt, there was a marked increase in cardiac index, (from 3.78 +/- 0.4 to 5.86 +/- 0.4 1/min. m2, p less than 0.01), and mean pulmonary artery pressure (from 17.3 +/- 1.9 to 23.3 +/- 1.5 mmHg, p less than 0.05), while a significant decrease in systemic vascular resistances (from 1086 +/- 116 to 694 +/- 52, p less than 0.05) was observed. In all patients there was a drop in arterial oxygen tension (PaO2) (from 76 +/- 3 to 67 +/- 3 torr, p less than 0.01) and an increase in venous admixture (Qsp/Qt) from 13.1 +/- 2 to 18.9 +/- 2%, p less than 0.01). The comparable increase in cardiac output and in venous admixture produced by opening the peritoneovenous shunt, might be related to the massive transfusion of ascitic fluid into the intravascular compartment. It is therefore concluded that this impairment of tas exchange further support discarding an appropriate amount of ascitic fluid at the time of shunt insertion.
L S Brandi; M Grana; F D'Elia; M Ferrari; M Oleggini; M Carmellini; A Pietrabissa; F Mosca
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Italian journal of surgical sciences / sponsored by Società italiana di chirurgia     Volume:  18     ISSN:  0392-3525     ISO Abbreviation:  Ital J Surg Sci     Publication Date:  1988  
Date Detail:
Created Date:  1989-03-28     Completed Date:  1989-03-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8213451     Medline TA:  Ital J Surg Sci     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  137-42     Citation Subset:  IM    
Istituto di Clinica Chirurgica, Unità di Terapia Intensiva, Università di Pisa.
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MeSH Terms
Ascites / physiopathology*,  therapy
Liver Cirrhosis / physiopathology*,  therapy
Middle Aged
Peritoneovenous Shunt*
Pulmonary Gas Exchange*

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