Document Detail


Acute effects of nicotine content in cigarettes on coronary flow velocity and coronary flow reserve in men.
MedLine Citation:
PMID:  9832107     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We investigated the acute effects of smoking on coronary flow reserve in terms of the nicotine content of cigarettes in 21 smokers. Coronary flow velocity was measured with a Doppler flow wire. Subjects smoked cigarettes containing >1 mg nicotine (n = 8, group 1) or <1 mg (n = 6, group 2). Subjects in the control group mimicked smoking without a cigarette (n = 7). Coronary flow reserve decreased after smoking in group 1, but not in group 2 or the control group. This reduction may have mediated nicotine or some other unknown substances influenced by smoking.
Authors:
T Tanaka; Y Oka; I Tawara; T Sada; Y Kira
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  82     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1998-12-14     Completed Date:  1998-12-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1275-8, A9     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, Showa General Hospital, Kodaira-City, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Flow Velocity / drug effects
Chromatography, High Pressure Liquid
Coronary Circulation / drug effects*
Epinephrine / blood
Female
Hemodynamics / drug effects
Humans
Male
Middle Aged
Nicotine / blood,  pharmacology*
Norepinephrine / blood
Smoking*
Sympathomimetics / blood
Chemical
Reg. No./Substance:
0/Sympathomimetics; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 54-11-5/Nicotine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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