| Acute effects in vivo of anti-insulin serum on rates of fatty acid synthesis and activities of acetyl-coenzyme A carboxylase and pyruvate dehydrogenase in liver and epididymal adipose tissue of fed rats. | |
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MedLine Citation:
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PMID: 12755 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Plasma insulin concentrations in fed rats were altered acutely by administration of glucose or anti-insulin serum. Rates of fatty acid synthesis in adipose tissue and liver were estimated from the incorporation of 3H from 3H2O. In the adipose tissue dehydrogenase and acetyl-CoA carboxylase were evident. In liver, although changes in rates of fatty acid synthesis were found, the initial activity of pyruvate dehydrogenase did not alter, but small parallel changes in acetyl-CoA carboxylase activity were observed. |
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Authors:
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D Stansbie; R W Brownsey; M Crettaz; R M Denton |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Biochemical journal Volume: 160 ISSN: 0264-6021 ISO Abbreviation: Biochem. J. Publication Date: 1976 Nov |
Date Detail:
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Created Date: 1977-02-26 Completed Date: 1977-02-26 Revised Date: 2010-08-31 |
Medline Journal Info:
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Nlm Unique ID: 2984726R Medline TA: Biochem J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 413-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetyl-CoA Carboxylase
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metabolism* Adipose Tissue / enzymology, metabolism* Animals Fatty Acids / biosynthesis* Glucose / pharmacology Insulin / blood*, immunology Ligases / metabolism* Liver / enzymology, metabolism* Male Pyruvate Dehydrogenase Complex / metabolism* Rats |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids; 0/Pyruvate Dehydrogenase Complex; 11061-68-0/Insulin; 50-99-7/Glucose; EC 6.-/Ligases; EC 6.4.1.2/Acetyl-CoA Carboxylase |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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