| Acute effect of intravenous magnesium sulfate on airway obstruction of asthmatic patients. | |
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MedLine Citation:
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PMID: 3189965 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The bronchodilating effect of magnesium sulfate (MgSO4) was studied in ten asthmatic patients with moderate to severe airway obstruction. Two grams of MgSO4 or saline in double-blind crossover design was administered IV for 20 minutes (0.40 mmol/min) and forced expiratory capacity and forced expiratory volume in one second (FEV1) were studied at intervals. Only at the end of MgSO4 infusion did FEV1 increase significantly (109% of initial values). The bronchodilating effect was short lasting and far less than that observed after salbutamol. |
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Authors:
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G Rolla; C Bucca; E Caria; W Arossa; M Bugiani; L Cesano; A Caropreso |
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Publication Detail:
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Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Annals of allergy Volume: 61 ISSN: 0003-4738 ISO Abbreviation: Ann Allergy Publication Date: 1988 Nov |
Date Detail:
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Created Date: 1988-12-08 Completed Date: 1988-12-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372346 Medline TA: Ann Allergy Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 388-91 Citation Subset: IM |
Affiliation:
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Medical Clinic, University of Turin, Molinette Hospital, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Airway Obstruction / drug therapy Asthma / physiopathology* Female Humans Injections, Intravenous Magnesium / blood Magnesium Sulfate / administration & dosage* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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7439-95-4/Magnesium; 7487-88-9/Magnesium Sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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