| Acute effect of atorvastatin on coronary circulation measured by transthoracic Doppler echocardiography in patients without coronary artery disease by angiography. | |
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MedLine Citation:
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PMID: 15979441 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirty-two patients were randomly assigned to treatment with placebo or atorvastatin. The time-averaged peak diastolic velocity (APDV) of the left anterior descending artery without stenosis was measured by transthoracic Doppler echocardiography at rest and under hyperemic conditions before and 1 hour after treatment. APDV increased significantly in the atorvastatin group, at rest and under hyperemic conditions, and coronary flow velocity reserve also increased in the atorvastatin group compared with patients given placebo. Atorvastatin improved the blood flow velocity of the normal coronary artery <1 hour after administration in patients without coronary artery disease by angiography. |
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Authors:
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Toshihide Hinoi; Shusuke Matsuo; Futoshi Tadehara; Shuji Tsujiyama; Michio Yamakido |
Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The American journal of cardiology Volume: 96 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2005 Jul |
Date Detail:
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Created Date: 2005-06-27 Completed Date: 2005-08-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 89-91 Citation Subset: AIM; IM |
Affiliation:
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Department of Internal Medicine, Kure Kyosai Hospital, Hiroshima, Japan. t-hinoi@kure-kyosai.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anticholesteremic Agents / administration & dosage, pharmacology*, therapeutic use Coronary Angiography Coronary Circulation / drug effects* Echocardiography, Doppler Female Heptanoic Acids / administration & dosage, pharmacology*, therapeutic use Humans Male Middle Aged Placebos Pyrroles / administration & dosage, pharmacology*, therapeutic use Regional Blood Flow |
| Chemical | |
Reg. No./Substance:
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0/Anticholesteremic Agents; 0/Heptanoic Acids; 0/Placebos; 0/Pyrroles; 110862-48-1/atorvastatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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