Document Detail

Acute dystonia resulting from abrupt bupropion discontinuation.
MedLine Citation:
PMID:  17218049     Owner:  NLM     Status:  MEDLINE    
Acute dystonia is commonly associated with high-potency antipsychotics. Some cases of acute dystonia had been reported to be associated with antidepressant. However, only few reported cases are related to bupropion. As reported herein, the patient with major depression suffered from acute dystonia twice, which resulted from abrupt bupropion discontinuation. The first episode occurred when medicament was shifted from bupropion to duloxetine abruptly. The patient was requested with nothing per mouth (NPO) due to panendoscopic examination. Therefore, the second one emerged after the patient was suspended from two doses of bupropion. The symptoms of dysphagia, trismus and torticollis in these two episodes were resolved after bupropion reinstitution or biperiden injection. So far as we know by our documents, this is the first report concerning an acute dystonia resulting from bupropion discontinuation.
Hung-Yu Wang; Wen-Jiun Chou; Tsan-Yu Huang; Chi-Fa Hung
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-01-10
Journal Detail:
Title:  Progress in neuro-psychopharmacology & biological psychiatry     Volume:  31     ISSN:  0278-5846     ISO Abbreviation:  Prog. Neuropsychopharmacol. Biol. Psychiatry     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-30     Completed Date:  2007-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211617     Medline TA:  Prog Neuropsychopharmacol Biol Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  766-8     Citation Subset:  IM    
Kai-Suan Psychiatric Hospital, Taiwan, ROC.
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MeSH Terms
Antidepressive Agents, Second-Generation / adverse effects*,  therapeutic use
Bupropion / adverse effects*,  therapeutic use
Depressive Disorder, Major / drug therapy
Dystonia / chemically induced*
Middle Aged
Substance Withdrawal Syndrome*
Reg. No./Substance:
0/Antidepressive Agents, Second-Generation; 34841-39-9/Bupropion

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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