Document Detail

Acute critical ischaemia of the limb: a prospective evaluation.
MedLine Citation:
PMID:  2204549     Owner:  NLM     Status:  MEDLINE    
A total of 119 patients with acute peripheral arterial ischaemia were studied prospectively to validate the definition of acute critical ischaemia suggested by the working party of the International Vascular Symposium. The majority of the patients had primary treatment using thrombolytic therapy. Overall limb salvage after 30 days was achieved in 56% of the patients, 19% required amputations and 25% died. Comparisons of the outcome in patients with or without a distal neurosensory deficit (limb salvage 30% vs. 72%, P = 0.0001) and those with absent or audible Doppler ankle blood flow (limb salvage 37% vs. 78%, P = 0.0001) confirmed that the severity of the initial ischaemia was a significant indicator of prognosis. The definition of acute critical ischaemia as assessed by objective measurement of Doppler pressures has been validated and can be used to divide patients into groups with critical and sub-critical ischaemia with different prognoses.
J J Earnshaw; B R Hopkinson; G S Makin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of vascular surgery     Volume:  4     ISSN:  0950-821X     ISO Abbreviation:  Eur J Vasc Surg     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-10-16     Completed Date:  1990-10-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8709440     Medline TA:  Eur J Vasc Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  365-8     Citation Subset:  IM    
Department of Vascular Surgery, University Hospital, Nottingham, U.K.
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MeSH Terms
Acute Disease
Aged, 80 and over
Ischemia / diagnosis*,  physiopathology,  therapy
Leg / blood supply*
Middle Aged
Prospective Studies
Thromboembolism / diagnosis*,  physiopathology,  therapy
Comment In:
Eur J Vasc Surg. 1991 Feb;5(1):106-7   [PMID:  2009976 ]

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