Document Detail

Acute conjunctivitis. A comparison of fusidic acid viscous eye drops and chloramphenicol.
MedLine Citation:
PMID:  8333258     Owner:  NLM     Status:  MEDLINE    
Fucidic acid viscous eye drops 1% given twice daily was compared with chloramphenicol eye drops 0.5% given 6 times daily in patients with acute conjunctivitis. Patients were recruited from 38 general practitioners in Norway. The mean duration of treatment was 6.6 days for Fucidic acid, 6.2 days for chloramphenicol. There was no major differences between the two groups in the bacteriological findings, and there was no significant difference in response to treatment. The use of fusidic acid in a carbomer vehicle as in Fucithalmic, has proved to give a long-lasting antibiotic concentration in the tear fluid, which allows the preferable twice daily application.
I Hørven
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Acta ophthalmologica     Volume:  71     ISSN:  0001-639X     ISO Abbreviation:  Acta Ophthalmol (Copenh)     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-08-16     Completed Date:  1993-08-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370347     Medline TA:  Acta Ophthalmol (Copenh)     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  165-8     Citation Subset:  IM    
Department of Ophthalmology, Oslo University, National Hospital, Rikshospitalet, Norway.
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MeSH Terms
Acute Disease
Aged, 80 and over
Child, Preschool
Chloramphenicol / administration & dosage*,  therapeutic use
Conjunctivitis / drug therapy*,  microbiology
Double-Blind Method
Drug Administration Schedule
Eye Infections, Bacterial / drug therapy*
Fusidic Acid / administration & dosage*,  therapeutic use
Infant, Newborn
Middle Aged
Ophthalmic Solutions
Reg. No./Substance:
0/Ophthalmic Solutions; 56-75-7/Chloramphenicol; 6990-06-3/Fusidic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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