Document Detail

Acute confusion or altered mental state: consider nonconvulsive status epilepticus.
MedLine Citation:
PMID:  17684419     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The diagnosis of nonconvulsive status epilepticus (NCSE) is particularly challenging in elderly patients. Confusion, personality change, dysphasia, subtle motor activity and nystagmus may be the only presenting signs. OBJECTIVE: To review current knowledge about NCSE with special focus on older people. METHODS: Systematic review of the current literature via Medline search. CONCLUSION: Although prospective studies are still lacking, NCSE may be one of the most frequently missed diagnoses in patients presenting with altered mental status. Elderly patients are at particular risk of diagnostic errors because of the broad range of presentations of NCSE, significant comorbidities (especially cerebrovascular disease), limited awareness of this particular seizure emergency or difficulties with access to electroencephalography. Although diagnostic criteria and treatment remain controversial, the diagnosis of NCSE is important because it is potentially reversible.
Stefan Beyenburg; Christian E Elger; Markus Reuber
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-08-07
Journal Detail:
Title:  Gerontology     Volume:  53     ISSN:  1423-0003     ISO Abbreviation:  Gerontology     Publication Date:  2007  
Date Detail:
Created Date:  2008-05-08     Completed Date:  2008-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7601655     Medline TA:  Gerontology     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  388-96     Citation Subset:  IM    
Copyright Information:
Copyright 2007 S. Karger AG, Basel.
Department of Neurology, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg, USA.
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MeSH Terms
Anticonvulsants / therapeutic use
Confusion / etiology*
Diagnosis, Differential
Status Epilepticus / diagnosis*,  drug therapy
Reg. No./Substance:

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