Document Detail

Acute community-acquired pneumonia due to Aspergillus in presumably immunocompetent hosts: clues for recognition of a rare but fatal disease.
MedLine Citation:
PMID:  9726758     Owner:  NLM     Status:  MEDLINE    
This article reports a case of acute community-acquired pneumonia due to Aspergillus fumigatus in a healthy patient and reviews 11 previously reported cases occurring in presumably immunocompetent hosts. The diagnosis was delayed for all patients; mortality was 100%. Clues that might suggest Aspergillus as a pathogen in community-acquired pneumonia include a chest radiograph revealing diffuse infiltrates or new cavitation; lack of bacterial or viral cause; a preceding influenza A infection; and respiratory secretion cultures positive for Aspergillus. When these clues are present, the physician should consider an early biopsy of lung tissue. Increased recognition and more timely diagnosis in future cases will improve the outcome of this rare but fatal infection.
C J Clancy; M H Nguyen
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Chest     Volume:  114     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-09-15     Completed Date:  1998-09-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  629-34     Citation Subset:  AIM; IM    
University of Florida College of Medicine, Department of Medicine, Gainesville 32610, USA.
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MeSH Terms
Acute Disease
Aspergillosis / complications*
Aspergillus fumigatus / isolation & purification*
Child, Preschool
Community-Acquired Infections / diagnosis,  etiology,  microbiology
Fatal Outcome
Immunocompromised Host*
Lung / microbiology
Lung Diseases, Fungal / diagnosis,  etiology*,  microbiology
Middle Aged
Pneumonia / diagnosis,  etiology*,  microbiology
Radiography, Thoracic
Retrospective Studies

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