Document Detail


Acute and chronic toxicity of organophosphate monocrotophos to Daphnia magna.
MedLine Citation:
PMID:  19089713     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The acute and chronic toxicity of monocrotophos (MCP), the binary joint toxicity of MCP and bifenthrin (BF), and sodium dodecyl benzene sulfonate (SDBS) to Daphnia magna (D. magna) was evaluated. The 24 h-median effective concentration (24 h-EC(50)) and 48 h-median lethal concentration (48 h-LC(50)) of MCP towards D. magna were 161 and 388 micro g/L, respectively. In addition, the lowest-observed effective concentration (LOEC) and non-observed effective concentration (NOEC) of MCP to D. magna were 10 and 5 micro g/L, respectively. Furthermore, the chronic value (ChV) of MCP against D. magna was 7 micro g/L and the acute chronic ratio (ACR) was 55. The number of offspring per female and the intrinsic rate of natural increase (r) were identified as the parameters that were most sensitive to MCP. In addition, toxic unit (TU) analysis was employed to evaluate the joint toxicities. The calculated TU(mix) values of binary equitoxic mixtures of MCP + BF and MCP + SDBS were 1.47 and 1.63, respectively, which suggests that both equitoxic mixtures exert a limited antagonistic effect. The results of this study revealed that the toxic threshold of MCP towards D. magna is higher than its reported highest residue (4 micro g/L) in the ordinary aquatic environment, and that concurrent exposure to BF or SDBS may exert a slight antagonistic effect.
Authors:
Lumei Wang; Weihong Ye; Shanshan Zhou; Kunde Lin; Meirong Zhao; Weiping Liu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes     Volume:  44     ISSN:  1532-4109     ISO Abbreviation:  J Environ Sci Health B     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-17     Completed Date:  2009-02-26     Revised Date:  2009-07-21    
Medline Journal Info:
Nlm Unique ID:  7607167     Medline TA:  J Environ Sci Health B     Country:  United States    
Other Details:
Languages:  eng     Pagination:  38-43     Citation Subset:  IM    
Affiliation:
Institute of Environmental Science, Zhejiang University, Hangzhou, P R China.
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MeSH Terms
Descriptor/Qualifier:
Acute Toxicity Tests
Animals
Benzenesulfonates / toxicity
Daphnia / drug effects*,  growth & development,  metabolism
Insecticides / toxicity*
Monocrotophos / toxicity*
Phosphoric Acid Esters / toxicity*
Pyrethrins / toxicity
Toxicity Tests, Chronic
Water Pollutants, Chemical / toxicity*
Chemical
Reg. No./Substance:
0/Benzenesulfonates; 0/Insecticides; 0/Phosphoric Acid Esters; 0/Pyrethrins; 0/Water Pollutants, Chemical; 27176-87-0/dodecylbenzenesulfonic acid; 6923-22-4/Monocrotophos; 82657-04-3/bifenthrin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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