| Acute on chronic subdural hematoma as a rare complication in a microscopic polyangiitis patient receiving antithrombotic treatment. | |
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MedLine Citation:
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PMID: 19761727 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a 56-year-old man with microscopic polyangiitis (MPA) who developed acute exacerbation of a chronic subdural hematoma (SDH). Laboratory data demonstrated elevation of myeloperoxidase antineutrophil cytoplasmic antibody (MPOANCA) and rapidly progressing renal dysfunction. Renal biopsy showed crescentic glomerulonephritis (GN) with membranous nephropathy (MN). He was treated with corticosteroids, antithrombotic agents, and an immunosuppressant. One month after initiation of treatment, he had a mild headache. One month later, he developed acute SDH. Although he recovered completely after the operation, he finally died of bacterial infection. On autopsy, a scar of vasculitis was confirmed in the leptomeninges as well as in the kidney and lung. Although SDH is a rare complication in MPA, nephrologists must pay more attention to the initial symptoms before a hematoma attack such as headache, especially in patients using antithrombotic agents. |
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Authors:
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N Takahashi; H Kimura; R Kitai; M Sato; M Yoneda; C Yamamoto; D Mikami; M Kuriyama; T Kubota; H Itoh; H Yoshida |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical nephrology Volume: 72 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-09-18 Completed Date: 2009-12-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: Germany |
Other Details:
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Languages: eng Pagination: 211-5 Citation Subset: IM |
Affiliation:
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Department of General Medicine, Division of Nephrology, School of Medicine, Faculty of Medical Sciences, University of Fukui, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Fibrinolytic Agents
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adverse effects* Hematoma, Subdural, Acute / etiology* Hematoma, Subdural, Chronic / etiology* Humans Male Microscopic Polyangiitis / complications* Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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