| Acute and chronic effects of cadmium on blood homeostasis of an estuarine crab, Chasmagnathus granulata, and the modifying effect of salinity. | |
| | |
MedLine Citation:
|
PMID: 11285463 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Whole body oxygen consumption and some hemolymph parameters such as pH, partial pressure of gases, level of ions and lactate were measured in the estuarine crab Chasmagnathus granulata after both acute (96 h) and chronic (2 weeks) exposure to cadmium at concentrations ranging from 0.4 to 6.3 mg/l. In all instances, the crabs developed hemolymph acidosis, but no respiratory (increased PCO2) or lactate increases were evident. Hemolymph levels of sodium and calcium were always increased by cadmium exposure. The chronic toxicity of cadmium was enhanced at 12 per mil salinity, even causing a significantly higher mortality in comparison with the higher salinity (30 per mil ) used. A general metabolic arrest took place at 12 per mil salinity in the crabs chronically exposed to cadmium, as indicated by decreases of oxygen consumption and PCO2, an increase of PO2, along with no changes in lactate levels. These imbalances were associated with severe necrosis and telangiectasia in the respiratory gills, probably leading to respiratory impairment and finally histotoxic hypoxia and death of the animals. |
| | |
Authors:
|
E M Rodríguez; R Bigi; D A Medesani; V S Stella; L S Greco; P A Moreno; J M Monserrat; G N Pellerano; M Ansaldo |
Related Documents
:
|
11834113 - Blood lactate and stroke parameters during front crawl in elite swimmers with disability. 16365513 - Detection of lactate threshold by including haemodynamic and oxygen extraction data. 8087083 - Vasopressin in the nucleus tractus solitarius: a modulator of baroreceptor reflex contr... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] Volume: 34 ISSN: 0100-879X ISO Abbreviation: Braz. J. Med. Biol. Res. Publication Date: 2001 Apr |
Date Detail:
|
Created Date: 2001-04-04 Completed Date: 2001-06-07 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8112917 Medline TA: Braz J Med Biol Res Country: Brazil |
Other Details:
|
Languages: eng Pagination: 509-18 Citation Subset: IM |
Affiliation:
|
Departamento de Ciencias Biologicas, FCEyN, Pab. II, Universidad de Buenos Aires, Ciudad Universitaria, 1428 Buenos Aires, Argentina. enrique@bg.fcen.uba.ar |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Brachyura / drug effects*, physiology Cadmium / pharmacology*, toxicity Calcium / blood Hemolymph / chemistry, drug effects*, metabolism Homeostasis / drug effects* Lactates / blood Male Oxygen Consumption / drug effects Sodium / blood Sodium Chloride / pharmacology* |
| Chemical | |
Reg. No./Substance:
|
0/Lactates; 7440-23-5/Sodium; 7440-43-9/Cadmium; 7440-70-2/Calcium; 7647-14-5/Sodium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Incorporation of dietary trans monounsaturated fatty acids into tissues of Walker 256 tumor-bearing ...
Next Document: Effect of sodium carboxymethylcellulose and methylprednisolone on the healing of jejunal anastomoses...