| Acute changes in bladder volume produce minimal cardio-respiratory responses in lightly anesthetised humans. | |
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MedLine Citation:
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PMID: 10958096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To examine whether changes in bladder volume elicit reflex cardiovascular and respiratory responses in humans under general anesthesia with sevoflurane and nitrous oxide. METHODS: Fourteen patients free of autonomic disorders were anesthetized with sevoflurane 0.5% and nitrous oxide 60% in oxygen that were approximately equivalent to 0.9 MAC. Warmed saline (6 ml x kg(-1), 37 degrees C) was instilled into the pre-emptied urinary bladder, and then the bladder was kept distended for five minutes. Following the distension, the instilled saline was drained to the pre-instilled volume of the bladder Arterial blood pressure, respiratory flow, and intra-vesicle pressure were continuously measured, and mean arterial pressure, pulse rate, respiratory rate, tidal volume, and minute ventilation were estimated offline from these signals. RESULTS: Bladder emptying produced small decreases in mean blood pressure (from 83.4+/-4.3 to 80.0+/-4.4 mm Hg, mean +/- SE, P = 0.017) and pulse rate (from 72.2+/-2.9 to 69.4+/-2.7 bpm, mean +/- SEM, P = 0.004). Only minimal respiratory reflexes were invoked by the bladder volume changes. CONCLUSION: In lightly anesthetized humans, the acute changes in bladder volume produce only mild cardiovascular and respiratory responses. |
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Authors:
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T Ishikawa; J Sato; T Nishino |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Canadian journal of anaesthesia = Journal canadien d'anesthésie Volume: 47 ISSN: 0832-610X ISO Abbreviation: Can J Anaesth Publication Date: 2000 Aug |
Date Detail:
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Created Date: 2000-12-07 Completed Date: 2000-12-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8701709 Medline TA: Can J Anaesth Country: CANADA |
Other Details:
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Languages: eng Pagination: 786-91 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology, Chiba University School of Medicine, Japan. iteru@anesth01.m.chiba-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Anesthesia* Blood Pressure* Female Heart Rate* Humans Male Middle Aged Reflex Respiration* Urinary Bladder / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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