| Acute cerebral ischemia: evaluation with dynamic contrast-enhanced MR imaging and MR angiography. | |
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MedLine Citation:
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PMID: 1727307 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Dynamic contrast-enhanced T2-weighted magnetic resonance (MR) imaging and MR angiography (MRA) were used to evaluate cerebral blood volume and the intracranial arterial system in 34 patients within 48 hours after the onset of cerebral ischemia. In 24 of the patients, an abnormality identified on T2-weighted images corresponded to the acute clinical deficit. Intracranial MRA demonstrated occlusions or severe stenoses of major vessels supplying the area of infarction in 16 of these patients, and decreased blood volume correlated well with MRA abnormalities. Infarcts less than 2 cm in diameter were not reliably shown with MRA or blood volume studies. Correlation between lesions seen with MRA and decreased blood volume in acute infarcts was good, and both techniques demonstrated lesions early in the clinical course. By providing information about hemodynamics not available with conventional T1- or T2-weighted images, MRA and dynamic MR imaging could prove helpful in describing the pathophysiologic characteristics of stroke and in guiding early therapeutic intervention. |
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Authors:
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S Warach; W Li; M Ronthal; R R Edelman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 182 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1992 Jan |
Date Detail:
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Created Date: 1992-01-16 Completed Date: 1992-01-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 41-7 Citation Subset: AIM; IM |
Affiliation:
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Harvard Medical School, Beth Israel Hospital, Boston, MA 02215. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Brain / pathology Brain Ischemia / diagnosis* Cerebral Arteries / pathology* Cerebrovascular Circulation / physiology Contrast Media Drug Combinations Female Gadolinium DTPA Humans Magnetic Resonance Imaging / methods* Male Meglumine / diagnostic use Middle Aged Organometallic Compounds / diagnostic use Pentetic Acid / diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Drug Combinations; 0/Organometallic Compounds; 6284-40-8/Meglumine; 67-43-6/Pentetic Acid; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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