Document Detail

Acute brain swelling in cerebral embolization model of rats. I: Epidural pressure monitoring.
MedLine Citation:
PMID:  8059326     Owner:  NLM     Status:  MEDLINE    
The authors measured epidural pressure of rats using a microballoon to monitor brain swelling after cerebral embolism. Rats with embolization of the major cerebral artery frequently demonstrated acute brain swelling. Within 5 hours of embolization, the increase in epidural pressure was 29.7 +/- 20.3 mm Hg (mean +/- SD), ranging from 3 to 68 mm Hg. The increase in epidural pressure tended to reach a near-maximal value within 30 minutes of embolization and thereafter stayed at that point until the end of the experiment. These results suggest that measuring epidural pressure can quantitatively assess acute brain swelling in rats.
K Yamane; T Shima; Y Okada; T Takeda; T Uozumi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgical neurology     Volume:  41     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  1994 Jun 
Date Detail:
Created Date:  1994-09-15     Completed Date:  1994-09-15     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  477-81     Citation Subset:  IM    
Department of Neurosurgery, Chugoku Rousai Hospital, Hiroshima, Japan.
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MeSH Terms
Acute Disease
Balloon Dilatation
Blood Pressure / physiology
Brain Edema / physiopathology*
Disease Models, Animal
Intracranial Pressure / physiology*
Monitoring, Physiologic
Rats, Wistar
Time Factors

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