Document Detail

Acute bacterial meningitis in adults. A 20-year overview.
MedLine Citation:
PMID:  9046894     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Most clinical overviews of acute bacterial meningitis have either focused on children or all age groups combined, although the disease poses serious problems in the adult population. OBJECTIVE: To study the clinical and microbiological features of adult bacterial meningitis in Iceland, as a representative of the average European or North American community. PATIENTS AND METHODS: Data on a total of 132 cases in 127 patients (age, > or = 16 years) who were diagnosed as having acute bacterial meningitis in Iceland during the years 1975 to 1994 were collected from patient and laboratory records. Complete hospital records were found for 119 of the 132 cases identified. RESULTS: The annual incidence was 1.7/100,000 to 7.2/ 100,000 inhabitants (mean, 3.8/100,000). The most common causative organisms were Neisseria meningitidis (56%), Streptococcus pneumoniae (20%), Listeria monocytogenes (6%), and Haemophilus influenzae (5%). Neisseria meningitidis caused 93% of the infections in the 16- to 20-year-old age group, but it caused only 25% of the infections in patients aged 45 years or older. Listeria monocytogenes caused 14% of these cases. Cases of nosocomial and recurrent meningitis were rare. A significant underlying illness or condition was present in 39% of the patients. The mean mortality was 19.7%, and it did not change during the study period. CONCLUSIONS: In a study that involved all adult patients with bacterial meningitis in a single country for 2 decades, meningococci and pneumococci were the most frequent causative agents. However, meningococci were responsible for only one fourth of the cases among adult patients aged 45 years or older, most of these cases were caused by pneumococci and Listeria. Despite modern medical developments, approximately 20% of adult patients with bacterial meningitis died.
B Sigurdardóttir; O M Björnsson; K E Jónsdóttir; H Erlendsdóttir; S Gudmundsson
Related Documents :
23986964 - How to re-seal previously sealed dentin.
23352114 - Aphasia predicts unfavorable outcome in mild ischemic stroke patients and prompts throm...
25007694 - Comparison of the 'sniffing the morning air' position and simple head extension for glo...
24974854 - Combination of lidocaine suppository and periprostatic nerve block during transrectal p...
24105314 - The acute prescription of oxygen in orthopaedic trauma patients.
22124514 - Ability to return to driving after major lower limb amputation.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  157     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1997 Feb 
Date Detail:
Created Date:  1997-03-19     Completed Date:  1997-03-19     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  425-30     Citation Subset:  AIM; IM    
University of Iceland Medical School, Landspitalinn (National University Hospital), Reykjavík, Iceland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acute Disease
Diagnosis, Differential
Iceland / epidemiology
Meningitis, Bacterial* / cerebrospinal fluid,  complications,  diagnosis,  epidemiology,  microbiology,  mortality,  therapy
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Diagnosis and treatment of sleep apnea within the community. The Walla Walla Project.
Next Document:  Phalangeal bone density and hip fracture risk.