| Acute ascending necrotizing myelitis in Okinawa caused by herpes simplex virus type 2. | |
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MedLine Citation:
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PMID: 1899169 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of rapidly progressing ascending myelitis was necropsied. Necrosis was present throughout the whole length of the spinal cord and involved both the grey and white matter randomly. The perivascular lymphocytic infiltration in the spinal cord in the present case was more pronounced than that in the previously reported two cases of necrotizing myelopathy associated with malignancy. Using immunoperoxidase staining the presence of herpes simplex virus type 2 (HSV 2) antigen was demonstrated. Electron microscopic examinations revealed large numbers of HSV particles in the spinal cord. HSV 2 may be a common aetiological agent of necrotizing myelopathy and myelitis in Okinawa, an HSV 2 endemic area. In the present case, the necrosis was mainly found in the spinal cord but was also observed, to a very limited extent, in the brain. |
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Authors:
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T Iwamasa; H Yoshitake; H Sakuda; Y Kamada; M Miyazato; Y Utsumi; A Nakamura |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Virchows Archiv. A, Pathological anatomy and histopathology Volume: 418 ISSN: 0174-7398 ISO Abbreviation: Virchows Arch A Pathol Anat Histopathol Publication Date: 1991 |
Date Detail:
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Created Date: 1991-02-26 Completed Date: 1991-02-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8302198 Medline TA: Virchows Arch A Pathol Anat Histopathol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 71-5 Citation Subset: IM |
Affiliation:
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Department of Pathology, Ryukyu University School of Medicine, Okinawa, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Antigens, Viral / analysis Herpes Simplex* / immunology, pathology Herpesviridae Humans Immunohistochemistry Male Microscopy, Electron Middle Aged Myelitis / microbiology*, pathology Necrosis Pacific Islands Spinal Cord / pathology |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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