Document Detail

Acute arterial thrombosis of the lower extremity. Its natural history contrasted with arterial embolism.
MedLine Citation:
PMID:  6732488     Owner:  NLM     Status:  MEDLINE    
We compared a group of 52 patients with acute lower extremity ischemia secondary to arterial thrombosis with a series of 220 patients with peripheral embolism who were seen at the Massachusetts General Hospital, Boston, from 1967 through 1980. The conditions of patients with arterial thrombosis were misdiagnosed as acute embolism at a rate of 20%. Mortality in the patients with embolism was significantly higher. While patients with acute embolism were routinely treated with embolectomy, two thirds of the patients with thrombotic occlusion required surgery during their initial hospitalization for ongoing severe ischemia. More than half of these operations were carried out as emergency procedures. Limb salvage in surgically treated patients with arterial thrombosis was inferior to that seen with embolism. Early revascularization for acute thrombosis was carried out with a 30-day patency rate of 82%. While the mortality associated with acute thrombosis was significantly lower than that seen with peripheral embolism, the risk of major amputation was 35%. There should be no reluctance to proceed with indicated vascular reconstruction in the setting of acute limb ischemia secondary to arterial thrombosis.
R P Cambria; W M Abbott
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Archives of surgery (Chicago, Ill. : 1960)     Volume:  119     ISSN:  0004-0010     ISO Abbreviation:  Arch Surg     Publication Date:  1984 Jul 
Date Detail:
Created Date:  1984-07-20     Completed Date:  1984-07-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9716528     Medline TA:  Arch Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  784-7     Citation Subset:  AIM; IM    
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MeSH Terms
Acute Disease
Arterial Occlusive Diseases / complications,  mortality*,  surgery
Arteriosclerosis / complications
Atrial Fibrillation / complications
Coronary Disease / complications
Diagnosis, Differential
Embolism / complications,  mortality*,  surgery
Leg / blood supply*,  surgery
Thrombosis / complications,  mortality*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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