Document Detail

Acute allergic contact dermatitis due to para-phenylenediamine after temporary henna painting.
MedLine Citation:
PMID:  14684936     Owner:  NLM     Status:  MEDLINE    
The use of temporary natural henna painting for body adornment and hair dyeing is very common in several countries of the Indian subcontinent, Middle East, and North Africa, and the fad is spreading in other parts of the world. Several cases of para-phenylenediamine (PPD) contaminated, temporary traditional/natural henna induced sensitization and acute allergic reaction have been reported, along with occasional serious long term and rare fatal consequences. We report here a 17-year-old girl with blisters over her hands of five-days duration that appeared within 72 hours of applying a temporary henna paint to her hands during a social occasion. Similar lesions were noted on her face. She had previously applied black henna only once, a year earlier without developing any lesions. Clinical diagnosis of acute allergic contact dermatitis (ACD) was made. After a short course of oral corticosteroids, topical mometasone furaote 1.0% cream, and oral antihistamines, the lesions healed completely over the next four weeks leaving post-inflammatory hypopigmentation. Patch testing done with standard European battery, PPD 1% in petrolatum, and commercially available natural henna powder revealed a 3+ reaction to PPD at 48 hours. No reaction was seen at the natural henna site. Awareness of the condition among physicians and the public and regulation regarding warnings of the risks of using such products is urgently warranted.
Al-Mutairi Nawaf; Arun Joshi; Osama Nour-Eldin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of dermatology     Volume:  30     ISSN:  0385-2407     ISO Abbreviation:  J. Dermatol.     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-12-19     Completed Date:  2004-01-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7600545     Medline TA:  J Dermatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  797-800     Citation Subset:  IM    
Department of Dermatology, Farwaniya Hospital, Kuwait.
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MeSH Terms
Allergens / adverse effects*
Dermatitis, Allergic Contact / diagnosis*,  etiology,  pathology
Diagnosis, Differential
Facial Dermatoses / chemically induced,  diagnosis*,  pathology
Hand Dermatoses / chemically induced,  diagnosis*,  pathology
Naphthoquinones / adverse effects*
Patch Tests
Phenylenediamines / adverse effects*
Reg. No./Substance:
0/Allergens; 0/Naphthoquinones; 0/Phenylenediamines; 106-50-3/4-phenylenediamine; 83-72-7/lawsone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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