| Acute abdominal pain: the value of liver function tests in suspected cholelithiasis. | |
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MedLine Citation:
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PMID: 2810159 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Over a 4-year period, prospective data were collected on 311 patients with suspected acute cholecystitis. By identifying the diversity of conditions which can masquerade as acute cholecystitis, we have examined the role of biochemical liver function tests in the diagnosis and management of these patients. The initial clinical diagnosis of acute cholecystitis was confirmed in 229 patients (73.6%). Of those patients on whom liver function tests were performed, 76.3% (206/270) were confirmed to have cholecystitis and 69.9% (144/206) of these had some evidence of liver dysfunction. In the group of patients (64/270) with other diagnoses on whom liver function tests were performed, significantly fewer (57.8%, 37/64) had abnormal liver function tests (P less than 0.05). This is of little clinical value since normal liver function does not exclude cholecystitis (predictive value of negative test = 30.3%). In proven cases of cholecystitis, there was a significantly increased incidence of liver dysfunction when ductal calculi were present. Using the information obtained from this study, an investigative protocol is proposed which may substantially reduce the rate of misdiagnosis of patients with abdominal pain suggestive of cholelithiasis. |
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Authors:
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M G Dunlop; P M King; A A Gunn |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of the Royal College of Surgeons of Edinburgh Volume: 34 ISSN: 0035-8835 ISO Abbreviation: J R Coll Surg Edinb Publication Date: 1989 Jun |
Date Detail:
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Created Date: 1989-12-21 Completed Date: 1989-12-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7503110 Medline TA: J R Coll Surg Edinb Country: SCOTLAND |
Other Details:
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Languages: eng Pagination: 124-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abdomen, Acute
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etiology* Cholecystitis / diagnosis Cholelithiasis / diagnosis* Humans Liver Function Tests |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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