Document Detail

Acute Twin-Twin Transfusion Syndrome in Labor: Pathophysiology and Associated Factors.
MedLine Citation:
PMID:  22081903     Owner:  NLM     Status:  Publisher    
Abstract Objective: To review reported cases of acute TTTS in monochorionic twin pregnancies to help define variants of disease and determine associated factors. Methods: PubMed literature review using the search terms, ?acute,? and ?twin transfusion.? Articles were reviewed for clinical factors. Reference lists were carefully assessed for any additional articles. In order to rule out sudden progression of chronic TTTS as the cause, gestational age ?31 weeks was chosen. Cases were classified into subsets of acute TTTS. Results: There were 150 publications from 1942-2010. There were 51 cases that were classified into 4 variants of acute TTTS. Four cases were difficult to classify, with hemoglobin levels that were high normal and low normal, high normal and anemic, or low normal and polycythemic. Three publications defined the incidence for acute perinatal TTTS of 1.8-5.5% of monochorionic twins. Common factors associated with acute perinatal TTTS included monochorionicity and labor. Conclusions: Monochorionicity and labor are common factors underlying the propensity to acute perinatal TTTS. A spectrum of severity is for acute TTTS was seen. Perinatal specialists and neonatologists should be aware of the possibility of acute TTTS during labor so rapid volume replacement can be performed for neonatal resuscitation.
Daniel W Skupski; George Sylvestre; Gian Carlo Di Renzo; Amos Grunebaum
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-14
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Professor, Obstetrics and Gynecology, Weill Cornell Medical College, Flushing, NY.
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