Document Detail


[Acute stroke treatment - an update].
MedLine Citation:
PMID:  20927688     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An optimised prehospital management is important for acute stroke patients. A structured admittance to a stroke centre increases the rate of thrombolysis four-fold. To achieve short door-to-needle-times (< 30 min) a multi-disciplinary approach is necessary. Elderly stroke patients benefit from stroke unit therapy as do the younger patients. Blood pressure management is important during the first 24 hours after thrombolysis. Systolic blood pressures between 140 - 150 mmHg correlate with low bleeding rates. A subgroup analysis of the ECASS III study shows that a broad range of patients can be treated safely and efficiently in the 3 - 4.5 hour time window. Endovascular recanalisation therapy achieves high recanalisation rates. Whether these will be responsible for a significantly better outcome has to be shown in future randomised trials.
Authors:
J Röther; G F Hamann
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Publication Detail:
Type:  English Abstract; Journal Article; Review     Date:  2010-10-06
Journal Detail:
Title:  Fortschritte der Neurologie-Psychiatrie     Volume:  78     ISSN:  1439-3522     ISO Abbreviation:  Fortschr Neurol Psychiatr     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-07     Completed Date:  2011-01-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8103137     Medline TA:  Fortschr Neurol Psychiatr     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  566-71     Citation Subset:  IM    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
Neurologische Klinik, Asklepios Klinik Altona, Hamburg. j.roether@asklepios.com
Vernacular Title:
Schlaganfall akut - ein Update.
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MeSH Terms
Descriptor/Qualifier:
Aged
Emergency Medical Services
Fibrinolytic Agents / therapeutic use
Hospital Units
Humans
Neuroprotective Agents / therapeutic use
Stroke / diagnosis,  drug therapy,  therapy*
Thrombolytic Therapy
Tissue Plasminogen Activator / therapeutic use
Treatment Outcome
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents; 0/Neuroprotective Agents; EC 3.4.21.68/Tissue Plasminogen Activator

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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