Document Detail


Acute stroke patients have occult malignancy more often than expected.
MedLine Citation:
PMID:  20668384     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of the present study was to investigate the frequency of having occult malignancy in patients with acute ischemic stroke and their clinical characteristics. We retrospectively enrolled 1,714 consecutive ischemic stroke patients within 7 days of onset. The patients were divided into two groups: the Non-M group had no malignancy, and the M group had malignancy. We compared the clinical characteristics of the two groups. Of 1,714 ischemic stroke patients, 51 patients (3.0%; M group) were newly diagnosed as having malignancy. The M group was significantly older than the Non-M group (p = 0.009). Hemoglobin (Hb) was less and D-dimer was higher in the M group than in the Non-M group (p < 0.001). The patients with both D-dimer >or=1.3 ng/dl and Hb <12.8 g/dl more frequently had occult malignancy than patients without (p = 0.0088).
Authors:
Jyunichi Uemura; Kazumi Kimura; Kensaku Sibazaki; Takeshi Inoue; Yasuyuki Iguchi; Shinji Yamashita
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Publication Detail:
Type:  Journal Article     Date:  2010-07-29
Journal Detail:
Title:  European neurology     Volume:  64     ISSN:  1421-9913     ISO Abbreviation:  Eur. Neurol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-03     Completed Date:  2010-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  140-4     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 S. Karger AG, Basel.
Affiliation:
Department of Stroke Medicine, Kawasaki Medical School, Kurashiki, Japan. uemuratrail @ yahoo.co.jp
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Aged
Chi-Square Distribution
Female
Fibrin Fibrinogen Degradation Products / metabolism
Hematologic Neoplasms / diagnosis*,  epidemiology*
Hemoglobins / metabolism
Humans
Male
Prevalence
ROC Curve
Retrospective Studies
Risk Factors
Statistics, Nonparametric
Stroke / diagnosis*,  epidemiology*
Chemical
Reg. No./Substance:
0/Fibrin Fibrinogen Degradation Products; 0/Hemoglobins; 0/fibrin fragment D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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