Document Detail


Acute Responses to Intermittent and Continuous Exercise in Heart Failure Patients.
MedLine Citation:
PMID:  23007142     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: The purpose of this study was to compare cardiopulmonary responses, exercise adherence, tolerance, and safety of optimized high-intensity interval exercise (HIIE) compared with moderate-intensity continuous exercise (MICE) in patients with heart failure and reduced ejection fraction (HFREF). METHODS: Twenty patients with HFREF (aged 61 ± 9.9 years) were randomly assigned to HIIE corresponding to 2 × 8 minutes of 30-second intervals at 100% of peak power output and 30-second passive recovery intervals and to a 22-minute MICE corresponding to 60% of peak power output. Gas exchange, electrocardiogram, and blood pressure were measured continuously. Cardiac troponin T (cTnT), C-reactive protein (CRP), and brain natriuretic peptide (BNP) were measured before, 20 minutes after, and 24 hours after HIIE and MICE. RESULTS: Cardiopulmonary responses did not differ between MICE and HIIE. Higher exercise adherence and efficiency were observed on HIIE with a similar perceived exertion and time spent above 90% of peak oxygen consumption compared with MICE. Neither HIIE nor MICE caused any significant arrhythmias or increased CRP, BNP, or cTnT. CONCLUSIONS: Compared with MICE, HIIE demonstrated a higher exercise adherence and was well tolerated in patients with HFREF, while still providing a high-level physiological stimulus and leaving indices of inflammation (CRP), myocardial dysfunction (BNP), and myocardial necrosis (cTnT) unaffected.
Authors:
Eve Normandin; Anil Nigam; Philippe Meyer; Martin Juneau; Thibaut Guiraud; Laurent Bosquet; Asmaa Mansour; Mathieu Gayda
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-21
Journal Detail:
Title:  The Canadian journal of cardiology     Volume:  -     ISSN:  1916-7075     ISO Abbreviation:  Can J Cardiol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8510280     Medline TA:  Can J Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.
Affiliation:
Cardiovascular Prevention and Rehabilitation Centre (Centre ÉPIC), Montreal Heart Institute, University of Montreal, Montreal, Québec, Canada; Research Centre, Montreal Heart Institute, University of Montreal, Montreal, Québec, Canada; Department of Kinesiology, University of Montreal, Montreal, Québec, Canada.
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