| Acute Responses to Intermittent and Continuous Exercise in Heart Failure Patients. | |
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MedLine Citation:
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PMID: 23007142 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: The purpose of this study was to compare cardiopulmonary responses, exercise adherence, tolerance, and safety of optimized high-intensity interval exercise (HIIE) compared with moderate-intensity continuous exercise (MICE) in patients with heart failure and reduced ejection fraction (HFREF). METHODS: Twenty patients with HFREF (aged 61 ± 9.9 years) were randomly assigned to HIIE corresponding to 2 × 8 minutes of 30-second intervals at 100% of peak power output and 30-second passive recovery intervals and to a 22-minute MICE corresponding to 60% of peak power output. Gas exchange, electrocardiogram, and blood pressure were measured continuously. Cardiac troponin T (cTnT), C-reactive protein (CRP), and brain natriuretic peptide (BNP) were measured before, 20 minutes after, and 24 hours after HIIE and MICE. RESULTS: Cardiopulmonary responses did not differ between MICE and HIIE. Higher exercise adherence and efficiency were observed on HIIE with a similar perceived exertion and time spent above 90% of peak oxygen consumption compared with MICE. Neither HIIE nor MICE caused any significant arrhythmias or increased CRP, BNP, or cTnT. CONCLUSIONS: Compared with MICE, HIIE demonstrated a higher exercise adherence and was well tolerated in patients with HFREF, while still providing a high-level physiological stimulus and leaving indices of inflammation (CRP), myocardial dysfunction (BNP), and myocardial necrosis (cTnT) unaffected. |
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Authors:
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Eve Normandin; Anil Nigam; Philippe Meyer; Martin Juneau; Thibaut Guiraud; Laurent Bosquet; Asmaa Mansour; Mathieu Gayda |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-21 |
Journal Detail:
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Title: The Canadian journal of cardiology Volume: - ISSN: 1916-7075 ISO Abbreviation: Can J Cardiol Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-9-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8510280 Medline TA: Can J Cardiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Cardiovascular Prevention and Rehabilitation Centre (Centre ÉPIC), Montreal Heart Institute, University of Montreal, Montreal, Québec, Canada; Research Centre, Montreal Heart Institute, University of Montreal, Montreal, Québec, Canada; Department of Kinesiology, University of Montreal, Montreal, Québec, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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