Document Detail

Acute oral potassium overdose: the role of hemodialysis.
MedLine Citation:
PMID:  20721655     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Hyperkalemia is a common condition, particularly in the setting of renal dysfunction. Hyperkalemia due to intentional oral potassium overdose is not commonly reported.
CASE REPORT: We present a case of acute intentional potassium overdose in a patient with normal renal function resulting in significant hyperkalemia, with a maximum serum potassium concentration of 11 mEq/L. Despite an initial course complicated by various unstable cardiac rhythms, including ventricular tachycardia, ventricular fibrillation, and pulseless electrical activity, the patient was discharged from the hospital neurologically intact. Treatment for hyperkalemia included hemodialysis.
DISCUSSION: The role of dialysis in potassium overdose is poorly defined.
CONCLUSION: Based on this case and a review of the medical literature, we recommend hemodialysis for cases of potassium overdose with hemodynamic instability and significantly elevated serum potassium concentrations that do not respond promptly to medical therapy. Hemodialysis should also be considered in cases with underlying renal dysfunction.
George M Bosse; Melissa A Platt; Stephen D Anderson; Michael W Presley
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Journal of medical toxicology : official journal of the American College of Medical Toxicology     Volume:  7     ISSN:  1937-6995     ISO Abbreviation:  J Med Toxicol     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-14     Completed Date:  2011-07-19     Revised Date:  2013-07-31    
Medline Journal Info:
Nlm Unique ID:  101284598     Medline TA:  J Med Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  52-6     Citation Subset:  IM    
Copyright Information:
© American College of Medical Toxicology 2010
Department of Emergency Medicine, University of Louisville, 530 S. Jackson Street, Louisville, KY, 40202, USA.
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MeSH Terms
Administration, Oral
Arrhythmias, Cardiac / etiology
Drug Overdose
Hyperkalemia / blood,  physiopathology,  therapy*
Middle Aged
Potassium / administration & dosage,  poisoning*
Renal Dialysis*
Suicide, Attempted*
Treatment Outcome
Reg. No./Substance:

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