Document Detail

Acute Marchiafava-Bignami Disease with Extensive Diffusion Restriction and Early Recovery: Case Report and Review of the Literature.
MedLine Citation:
PMID:  23253188     Owner:  NLM     Status:  Publisher    
Marchiafava-Bignami disease (MBD) is a neurological disorder that has been found to be associated with chronic alcoholism and malnutrition. MBD classically results in acute edema and demyelination of the corpus callosum. Edema of the complete corpus callosum has been described to be an unfavorable prognostic factor. We present an acute onset of MBD with diffusion restriction of the complete corpus callosum and symmetric bilateral extension into the semioval center, that almost completely resolved clinically as well as in MRI only 3 days later. With early detection and treatment, the prognosis of MBD may be good even in cases with severe diffusion restriction of the complete corpus callosum.
Holger Wenz; Philipp Eisele; Dimitrios Artemis; Alex Förster; Marc A Brockmann
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-17
Journal Detail:
Title:  Journal of neuroimaging : official journal of the American Society of Neuroimaging     Volume:  -     ISSN:  1552-6569     ISO Abbreviation:  J Neuroimaging     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9102705     Medline TA:  J Neuroimaging     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 by the American Society of Neuroimaging.
From the Department of Neuroradiology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany (HW, AF, MAB); and Department of Neurology, University Medical Center Mannheim, University of Heidelberg, Mannheim, Germany (PE, DA).
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