Document Detail


Acute lung injury in preterm newborn infants: mechanisms and management.
MedLine Citation:
PMID:  20692631     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Respiratory morbidity and mortality remain common in preterm infants. The immature preterm lung is especially prone to injury. This process often starts in-utero due to maternal chorioamnionitis, priming the lung for further injury in response to post-natal ventilation, oxygen and nosocomial infection. Pulmonary inflammation has been strongly implicated in the pathway leading to lung injury in this population of infants. Several therapeutic approaches have been attempted to prevent acute lung injury or to limit its progress. The mechanisms of acute lung injury in preterm infants; their clinical correlates and available therapeutic approaches are reviewed here.
Authors:
Mallinath Chakraborty; Eamon P McGreal; Sailesh Kotecha
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Paediatric respiratory reviews     Volume:  11     ISSN:  1526-0550     ISO Abbreviation:  Paediatr Respir Rev     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100898941     Medline TA:  Paediatr Respir Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  162-70; quiz 170     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Child Health, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom. chakrabortym@cardiff.ac.uk
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