| Acute Ibuprofen Intoxication: Report on a Case and Review of the Literature. | |
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MedLine Citation:
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PMID: 22835967 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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ABSTRACT: A fatality following the ingestion of ibuprofen is reported. Ibuprofen is a prototypical nonsteroidal anti-inflammatory drug widely prescribed as an analgesic, anti-inflammatory, and antipyretic agent. To date, there are few case reports of fatal overdose with ibuprofen, following ibuprofen self-poisoning or accidental overdose. We report the case of a 51-year-old man with medical history of psychiatric disease, who was brought to the emergency department by ambulance with a chief complaint of having taken large amounts of drugs in a suicide attempt.Multiple empty containers of medications (ibuprofen, meloxicam, celecoxib, risperidone, citalopram, ketorolac, bromazepam) were found at the scene. He died 4 hours after admission to the emergency department, despite vigorous supportive care. Toxicological analyses were performed using a gas chromatography/mass spectrometry technique. The estimated ibuprofen concentration in the plasma was 600 μg/mL; gastric content was 200 μg/mL for this compound. Our report describes results of the forensic investigation and discuss the review of the literature. |
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Authors:
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Maria Lodise; Fabio De Giorgio; Riccardo Rossi; Ernesto d'Aloja; Nadia Fucci |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-7-25 |
Journal Detail:
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Title: The American journal of forensic medicine and pathology Volume: - ISSN: 1533-404X ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-7-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8108948 Medline TA: Am J Forensic Med Pathol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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From the *Institute of Legal Medicine, School of Medicine, Catholic University of the Sacred Heart, Rome; and †Forensic Science Department, Cagliari University, Monserrato (CA), Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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