| Acute fatty liver of pregnancy in a Taiwanese tertiary care center: a retrospective review. | |
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MedLine Citation:
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PMID: 20708520 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the demographics, clinical presentations, laboratory findings, and maternal and fetal outcomes in patients with acute fatty liver of pregnancy. MATERIALS AND METHODS: A retrospective review was conducted of the records of pregnant patients with a diagnosis of acute fatty liver in a tertiary medical center over a 22-year period. RESULTS: Eighteen patients with acute fatty liver of pregnancy were recruited, all of whom developed the disease in the third trimester. Eleven women (61%) were primigravid and four (22%) had twin pregnancies; six (33%) were diagnosed antepartum, and the other 12 (67%) were diagnosed postpartum. There were two maternal deaths (11%) and four fetal deaths (18%). The most common complications apart from severe liver dysfunction were acute renal failure (83%), hypoglycemia (61%), and disseminated intravascular coagulation (61%). CONCLUSION: Women who become acutely ill during the third trimester of pregnancy should undergo tests for acute fatty liver of pregnancy, including laboratory tests for assessing liver function and coagulation profile. |
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Authors:
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Hui-Hsuan Lau; Yi-Yung Chen; Jian-Pei Huang; Chen-Yu Chen; Tsung-Hsien Su; Chie-Pein Chen |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Taiwanese journal of obstetrics & gynecology Volume: 49 ISSN: 1875-6263 ISO Abbreviation: Taiwan J Obstet Gynecol Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-08-16 Completed Date: 2010-12-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101213819 Medline TA: Taiwan J Obstet Gynecol Country: China |
Other Details:
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Languages: eng Pagination: 156-9 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Taiwan Association of Obstetrics and Gynecology. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Division of High Risk Pregnancy, Mackay Memorial Hospital, Taipei, Taiwan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Kidney Injury
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complications Adult Apgar Score Cesarean Section / statistics & numerical data Cholesterol / blood Disseminated Intravascular Coagulation / complications Fatty Liver / complications*, mortality Female Fibrinogen / analysis Humans Hyperuricemia / complications Hypoglycemia / complications Length of Stay / statistics & numerical data Leukocytosis / complications Live Birth Partial Thromboplastin Time Pregnancy Pregnancy Complications* Pregnancy Trimester, Third Prothrombin Time Retrospective Studies Stillbirth Taiwan |
| Chemical | |
Reg. No./Substance:
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57-88-5/Cholesterol; 9001-32-5/Fibrinogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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