Document Detail


Acute exercise improves physical sexual arousal in women taking antidepressants.
MedLine Citation:
PMID:  22403029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Antidepressants can impair sexual arousal. Exercise increases genital arousal in healthy women, likely due to increasing sympathetic nervous system (SNS) activity.
PURPOSE: Test if exercise increases genital arousal in women taking antidepressants, including selective serotonin reuptake inhibitors (SSRIs), which suppress SNS activity, and selective serotonin and norepinephrine reuptake inhibitors (SNRIs), which suppress the SNS less.
METHOD: Women reporting antidepressant-related sexual arousal problems (N = 47) participated in three counterbalanced sessions where they watched an erotic film while we recorded genital and SNS arousal. In two sessions, women exercised for 20 min, either 5 or 15 min prior to the films.
RESULTS: During the no-exercise condition, women taking SSRIs showed significantly less genital response than women taking SNRIs. Exercise prior to sexual stimuli increased genital arousal in both groups. Women reporting greater sexual dysfunction had larger increases in genital arousal post-exercise. For women taking SSRIs, genital arousal was linked to SNS activity.
CONCLUSIONS: Exercise may improve antidepressant-related genital arousal problems.
Authors:
Tierney A Lorenz; Cindy M Meston
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Annals of behavioral medicine : a publication of the Society of Behavioral Medicine     Volume:  43     ISSN:  1532-4796     ISO Abbreviation:  Ann Behav Med     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-11     Completed Date:  2012-09-17     Revised Date:  2014-09-09    
Medline Journal Info:
Nlm Unique ID:  8510246     Medline TA:  Ann Behav Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  352-61     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Antidepressive Agents / therapeutic use*
Depressive Disorder / drug therapy*,  physiopathology,  psychology
Erotica
Exercise / physiology,  psychology*
Female
Humans
Libido / physiology*
Plethysmography
Sympathetic Nervous System / physiopathology*
Vagina
Grant Support
ID/Acronym/Agency:
1F31MH085416/MH/NIMH NIH HHS; 1R01 HD051676/HD/NICHD NIH HHS; F31 MH085416/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
0/Antidepressive Agents
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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