| Acute demyelinating encephalomyelitis after anti-venom therapy in Russell's viper bite. | |
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MedLine Citation:
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PMID: 20237970 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Russell's viper is a commonly encountered venomous snake in India. Morbidity and mortality following envenomation and the treatment thereof are frequent. We report a rarely seen complication after a treated Russell's viper bite. CASE REPORT: A 36-year-old male farmer received 30 vials polyvalent anti-snake venom after a viper bite to his right leg. Improvement in initial hematemesis and circulatory shock was followed by acute renal failure managed with regular hemodialysis. He displayed no abnormalities on neurological examination at admission. Fourth day onwards his neurologic status started deteriorating with development of behavioral abnormalities, hemi-spatial neglect of left upper limb, paralysis of left facial nerve, left upper limb, and right lower limb. Acute disseminated encephalomyelitis was confirmed on magnetic resonance imaging (MRI) of brain with typical spectroscopic characteristics. High dose methyl prednisolone was administered and a rapid recovery followed. CONCLUSION: Russell's viper bite followed by treatment with antivenom may be complicated by the development of immune complex mediated demyelination and development of acute disseminated encephalomyelitis. MRI spectroscopy helps in early identification of demyelination and in a definite diagnosis. Treatment with corticosteroids was associated with resolution of symptoms in this case. |
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Authors:
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S Tripathy; P K Routray; A K Mohapatra; M Mohapatra; S C Dash |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of medical toxicology : official journal of the American College of Medical Toxicology Volume: 6 ISSN: 1556-9039 ISO Abbreviation: J Med Toxicol Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-30 Completed Date: 2010-11-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101284598 Medline TA: J Med Toxicol Country: United States |
Other Details:
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Languages: eng Pagination: 318-21 Citation Subset: IM |
Affiliation:
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Department of Anesthesia and Intensive Care, Kalinga Institute of Medical Sciences, Patia, Bhubaneswar, India. swagi7@rediffmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Animals Antivenins / adverse effects* Demyelinating Diseases / diagnosis, etiology* Encephalomyelitis / diagnosis, etiology* Humans Magnetic Resonance Imaging Male Russell's Viper* Snake Bites / therapy* Viper Venoms / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Antivenins; 0/Viper Venoms |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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