Document Detail

Acute Cervical Myelopathy Due To Presumed Fibrocartilaginous Embolism: A Case Report And Systematic Review of The Literature.
MedLine Citation:
PMID:  24901879     Owner:  NLM     Status:  Publisher    
INTRODUCTION:: Fibrocartilaginous embolism (FCE) is an uncommon cause of myelopathy that should be considered after more common causes have been ruled out.
OBJECTIVE:: This article presents a case report of a 50-year-old man with acute myelopathy attributed to fibrocartilaginous embolism and summarizes the clinical features of the disease by analyzing all of the published evidence.
DATA SOURCES AND EXTRACTION:: Two computerized literature searches (MEDLINE - Pubmed; EMBASE, the Cochrane Library) were performed. The search term used was "Fibrocartilaginous embolism". No language restrictions were applied. All articles were evaluated and key data extracted according to pre-defined criteria: patient's age, year of publication, localization of the embolism and type of vascular syndrome, clinical outcome, and time to death in the fatal cases.
RESULTS:: Fifty-two cases (39 biopsy-proven and 13 clinically diagnosed) were found in the literature. Median age at presentation was 37 (IQR: 19-53) and 56% were women. Median progression of symptoms was 6 hours (IQR 5-60 h), predominantly affecting the cervical spine (48%) by an arterial embolic source (56%).
CONCLUSIONS:: FCE is an unusual cause of spinal cord and cerebral ischemia with unknown incidence. Implementation of diagnostic imaging techniques and initial management of acute spinal disorders care in intensive care units might increase the incidence of disease antemortem. FCE should be considered in the differential diagnosis of ischemic spinal cord injury when no other causes can be identified, and especially when the onset is progressive over several hours.
Juan Pablo Cuello; Santiago Ortega-Gutierrez; Guillermo Linares; Sachin Agarwal; Alyson Cunningham; Jay P Mohr; Stephan A Mayer; Randolph S Marshall; Jan Claassen; Neeraj Badjatia; Mitchel S V Elkind; Kiwon Lee
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-6-4
Journal Detail:
Title:  Journal of spinal disorders & techniques     Volume:  -     ISSN:  1539-2465     ISO Abbreviation:  J Spinal Disord Tech     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2014-6-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140323     Medline TA:  J Spinal Disord Tech     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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