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Acute Cardiac Failure due to Intra-Atrial Mass Caused by Zygomycetes in an Immunocompromised Paediatric Patient.
MedLine Citation:
PMID:  20671981     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Cardiac zygomycosis can be a critical condition with sudden onset of severe congestive heart failure followed by severe hemodynamic deterioration. We report a fatal course of disseminated fungal infection with a massive intra-atrial thrombosis caused by a zygomycete, in a five year old boy treated for acute lymphoblastic leukaemia. In addition, we discuss the literature concerning infections caused by zygomycetes involving the heart. Prognosis is poor. A high index of suspicion and an aggressive diagnostic and therapeutic approach with the prompt start of preemptive antifungal therapy are key factors to improve outcome.
Authors:
G J van de Glind; C E M Gidding; C M W Verlaat; K Duthoi; A P C Backx; P E Verweij; A Warris
Publication Detail:
Type:  Journal Article     Date:  2010-07-04
Journal Detail:
Title:  Case reports in medicine     Volume:  2010     ISSN:  1687-9635     ISO Abbreviation:  Case Rep Med     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-30     Completed Date:  2011-07-14     Revised Date:  2013-02-21    
Medline Journal Info:
Nlm Unique ID:  101512910     Medline TA:  Case Rep Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  241791     Citation Subset:  -    
Affiliation:
Department of Pediatrics, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
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