Document Detail

Acupuncture and in vitro fertilization: a retrospective chart review.
MedLine Citation:
PMID:  23363307     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: In 2007, Craig et al. reported the results of a randomized controlled trial in which a standardized acupuncture protocol performed on the day of embryo transfer (ET) resulted in lower pregnancy rates after in vitro fertilization (IVF). Between 2005 and 2007, the Craig protocol was used by one of the authors (LHR) at an infertility clinic unaffiliated with the Craig et al. trial. The objective was to retrospectively review clinic records to evaluate the effect of the Craig protocol in both donor and nondonor IVF cycles on four outcomes: (1) live births; (2) biochemical pregnancies; (3) adverse outcomes; and (4) live births in nondonor cycles across age groups established by the Society for Assisted Reproductive Technology.
DESIGN: The study design was a retrospective chart review.
SETTING: The study was conducted at a private infertility clinic.
PATIENT(S): Patients underwent fresh, donor (N=70) or nondonor (N=402) IVF-ET.
INTERVENTION(S): The Craig protocol included the following points before ET: GV-20, CV-6, ST-29, SP-8, PC-6, LV-3; Shenmen and Brain on the left ear; and Uterus and Endocrine on the right ear. After transfer the points were LI-4, SP-10, ST-36, SP-6, KI-3; Uterus and Endocrine on the left ear; and Shenmen and Brain on the right ear.
MAIN OUTCOME MEASURE(S): Live births (LB) beyond 24 weeks' gestation was the main outcome measure.
RESULT(S): In nondonor IVF cycles, there were no differences in LB across age groups (odds ratio [OR]=1.04, 95% confidence interval [CI] 0.68-1.57), biochemical pregnancies (OR=0.60, 95% CI 0.27-1.33), or adverse outcomes (OR=0.63, 95% CI 0.31-1.26). In donor cycles, LB were higher in the acupuncture group (relative risk=1.31, 95% CI 1.02-1.71).
CONCLUSIONS: In this observational study, the Craig protocol was not found to lower IVF LB. In fact, the Craig protocol was associated with higher LB in donor cycles. These findings should be considered cautiously because more adequately powered, randomized research is needed.
Lee E Hullender Rubin; Michael S Opsahl; Lisa Taylor-Swanson; Deborah L Ackerman
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2013-01-30
Journal Detail:
Title:  Journal of alternative and complementary medicine (New York, N.Y.)     Volume:  19     ISSN:  1557-7708     ISO Abbreviation:  J Altern Complement Med     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-07-03     Completed Date:  2013-10-17     Revised Date:  2014-07-01    
Medline Journal Info:
Nlm Unique ID:  9508124     Medline TA:  J Altern Complement Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  637-43     Citation Subset:  IM    
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MeSH Terms
Acupuncture Therapy*
Embryo Transfer
Fertilization in Vitro*
Infant, Newborn
Infertility / therapy
Retrospective Studies
Grant Support

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