Document Detail

Actuarial survival and other events following valve surgery in octogenarians: comparison with an age-, sex-, and race-matched population.
MedLine Citation:
PMID:  1873039     Owner:  NLM     Status:  MEDLINE    
From January 1973 to December 1989, 54 patients over 80 years of age underwent an intracardiac repair which included a cardiac valve operation. There were 21 males and 33 females. Mean age at operation was 82 years, range 80-89 years. Fifty-two patients (96%) were in New York Heart Association functional class III or IV preoperatively. Six patients had undergone previous valve surgery (11%). There were eight hospital deaths (14.8%). Risk factors for hospital death included older age at repair (p = 0.008), increased total cardiopulmonary bypass time (p = 0.06), and, possibly, smaller aortic valve prosthesis (p = 0.10). All 46 hospital survivors were followed up at a mean of 28.8 months after hospital discharge. There were 11 late deaths (23.9%), occurring at a mean of 32.3 months postoperatively. Survival analysis indicated that increased age (p = 0.06) and increased pulmonary artery diastolic pressure preoperatively (p less than 0.07) were multivariate risk factors for overall mortality. Actuarial survival at 5 years was 44%, with no difference from survival in an age-, sex-, and race-matched population. We conclude that octogenarians in the modern era have good chance for survival following valvular surgery. As hazards for full anticoagulation were low in this series, if valve repair is not feasible, we presently recommend the use of mechanical valves in the elderly to reduce the requirement for late reoperation due to bioprosthesis degeneration.
L B McGrath; M S Adkins; C Chen; B M Bailey; D Graf; J Fernandez; G W Laub; S B Pollock
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery     Volume:  5     ISSN:  1010-7940     ISO Abbreviation:  Eur J Cardiothorac Surg     Publication Date:  1991  
Date Detail:
Created Date:  1991-09-25     Completed Date:  1991-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8804069     Medline TA:  Eur J Cardiothorac Surg     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  319-25     Citation Subset:  IM    
Department of Surgery, Deborah Heart and Lung Center, Brown Mills, New Jersey.
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MeSH Terms
Actuarial Analysis
Age Factors
Aged, 80 and over
Cardiopulmonary Bypass / mortality*
European Continental Ancestry Group
Follow-Up Studies
Heart Valve Prosthesis / mortality*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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