| Actual pacemaker longevity: the benefit of stimulation by automatic capture verification. | |
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MedLine Citation:
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PMID: 20230462 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: We evaluated the impact of an algorithm for automatic right ventricular (RV) stimulation compared to fixed-output pacing (FOP) stimulation on actual pacemaker longevity over a 9-year follow-up. METHODS: Prospective observation of 300 patients implanted with VDDR/DDDR pacemakers in 1999-2000 up to October 31, 2008. Sixty-one patients were paced by Autocapture pacing (ACP), 239 were paced by FOP; they were seen twice yearly at the pacemaker clinic. Factors known to affect pacemaker longevity were collected: median heart rate, %A&V paced activity, pacing output, and impedance. Patients dead before pacemaker replacement, lost to follow-up, or who developed permanent atrial fibrillation were excluded from analysis. RESULTS: One hundred twenty-six of three hundred patients completed the study. Adverse clinical events due to an increased RV threshold occurred in two FOP patients compared to none among ACP. Pacemaker replacement occurred in 1/34 ACP patients versus 60/92 FOP patients (P < 0.001). ACP was the single independent predictor of pacemaker longevity at multivariable analysis (hazard ratio = 0.03, P < 0.001) either in the overall population or in the specific patients subgroups (sick sinus syndrome, atrioventricular block, and neurally mediated syncope). CONCLUSIONS: Automatic verification of stimulation is reliable at long term, and warrants superior safety in the event of pacing threshold changes. It allows a significant longevity increase compared to FOP stimulation that may heavily impact the patients' quality of life and the cost of pacing therapy. Moreover, it is a fundamental technology in a strategy of remote patient and device monitoring, and may enable automatic device follow-up operated by trained, nonmedical personnel. |
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Authors:
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Mauro Biffi; Matteo Bertini; Davide Saporito; Matteo Ziacchi; Cristian Martignani; Igor Diemberger; Giuseppe Boriani |
Publication Detail:
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Type: Evaluation Studies; Journal Article Date: 2010-03-06 |
Journal Detail:
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Title: Pacing and clinical electrophysiology : PACE Volume: 33 ISSN: 1540-8159 ISO Abbreviation: Pacing Clin Electrophysiol Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-20 Completed Date: 2010-11-30 Revised Date: 2011-04-15 |
Medline Journal Info:
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Nlm Unique ID: 7803944 Medline TA: Pacing Clin Electrophysiol Country: United States |
Other Details:
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Languages: eng Pagination: 873-81 Citation Subset: IM |
Affiliation:
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Institute of Cardiology, University of Bologna, Bologna, Italy. mauro.biffi@aosp.bo.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Equipment Design Equipment Failure Analysis / statistics & numerical data* Heart Failure / prevention & control* Humans Italy Middle Aged Pacemaker, Artificial / statistics & numerical data* Therapy, Computer-Assisted / instrumentation*, statistics & numerical data* |
| Comments/Corrections | |
Comment In:
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Pacing Clin Electrophysiol. 2011 Mar;34(3):389; author reply 389-90
[PMID:
21382060
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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