Document Detail


Activity of some lysosomal enzymes in peritoneal macrophages of patients with end-stage renal failure treated by intermittent peritoneal dialysis.
MedLine Citation:
PMID:  1709899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acid phosphatase, beta-D-Glucuronidase and N-acetyl-beta-D-glucosaminidase were assessed cytochemically in peritoneal macrophages obtained from 50 patients with end-stage renal failure treated by intermittent peritoneal dialysis and from 30 control subjects with normal renal function. A statistically significant increase in beta-D-glucuronidase activity accompanied by a decrease in acid phosphatase activity were observed in peritoneal macrophages of dialysed patients, as compared with the control group. In patients with dialysis-associated peritonitis, the activity of N-acetyl-beta-D-glucosaminidase was significantly higher than that observed in the same patients during the complication-free period of the treatment.
Authors:
W Sułowicz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Folia haematologica (Leipzig, Germany : 1928)     Volume:  117     ISSN:  0323-4347     ISO Abbreviation:  Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch.     Publication Date:  1990  
Date Detail:
Created Date:  1991-07-03     Completed Date:  1991-07-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0374615     Medline TA:  Folia Haematol Int Mag Klin Morphol Blutforsch     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  663-7     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Medical Academy, Krakow, Poland.
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MeSH Terms
Descriptor/Qualifier:
Acetylglucosaminidase / metabolism*
Acid Phosphatase / metabolism*
Adult
Glucuronidase / metabolism*
Humans
Kidney Failure, Chronic / complications,  enzymology*,  therapy
Lysosomes / enzymology*
Macrophages / enzymology*
Peritoneal Dialysis*
Peritonitis / complications
Reference Values
Chemical
Reg. No./Substance:
EC 3.1.3.2/Acid Phosphatase; EC 3.2.1.31/Glucuronidase; EC 3.2.1.52/Acetylglucosaminidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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