Document Detail

Activity of multiple sclerosis during pregnancy and puerperium.
MedLine Citation:
PMID:  6476794     Owner:  NLM     Status:  MEDLINE    
The influence of pregnancy on multiple sclerosis was studied in 338 women by determining in each trimester of pregnancy and post partum the number of relapses and the corresponding relapse rate. Eighty-five relapses occurred in association with 199 pregnancies, most (65) in the postpartum period, and a low number of relapses (2) were recorded in the last trimester of pregnancy. Comparing the average exacerbation rate of the study group with that of patients with multiple sclerosis in Israel (0.28 relapses per person per year), we found a statistically significant decrease in the third trimester (0.04) and a high increase in the first three months post partum (0.82). This pattern of remissions at the end of pregnancy and exacerbations post partum is similar to that observed in other putative autoimmune diseases.
I Korn-Lubetzki; E Kahana; G Cooper; O Abramsky
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Annals of neurology     Volume:  16     ISSN:  0364-5134     ISO Abbreviation:  Ann. Neurol.     Publication Date:  1984 Aug 
Date Detail:
Created Date:  1984-10-25     Completed Date:  1984-10-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7707449     Medline TA:  Ann Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  229-31     Citation Subset:  IM    
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MeSH Terms
Multiple Sclerosis / diagnosis*
Pregnancy Complications / diagnosis*
Puerperal Disorders / diagnosis*

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