Document Detail


Activity monitoring in heart failure patients with cardiac resynchronization therapy.
MedLine Citation:
PMID:  18037741     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Cardiac resynchronization therapy (CRT) improves functional capacity in heart failure patients. This study aimed to prospectively analyze long-term device-based monitoring of physical activity in patients undergoing CRT. METHODS AND RESULTS: The Activity Log Index (ALI), calculated by CRT devices, represents the percentage of time when acceleration exceeds a threshold and monitors the physical activity. Data from 178 CRT patients (New York Heart Association III 91%, left ventricular ejection fraction 21+/-6%, left ventricular end-diastolic diameter 69+/-9 mm, QRS 159+/-27 ms, sinus rhythm 81%) were retrieved. The ALI increased from a baseline value of 3.6+/-2.0 to 11.2+/-4.6 (p<0.005) 104 weeks after initiation of CRT. A plateau was reached at approximately 12 weeks and thereafter ALI remained stable for up to 2 years. The magnitude of the changes in ALI was similar in patients with different etiologies and underlying rhythms. Despite similar values at baseline, elderly patients (>or=65 years) exhibited significantly lower ALI values than younger patients during the follow-up and at the plateau (9.5+/-4.2 vs 13.3+/-4.8, p<0.001). CONCLUSIONS: Device-based monitoring of physical activity in CRT patients is feasible. CRT resulted in a large and long-term increase in physical activity.
Authors:
Mihoko Kawabata; Cecilia Fantoni; Francois Regoli; Santi Raffa; Francesca Pastori; Simona Fratini; John Prentice; Helmut U Klein; Angelo Auricchio
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  71     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-26     Completed Date:  2008-02-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1885-92     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Medicine, Tokyo Medical and Dental University, Japan. mihoko_kawabata.cvm@tmd.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Aged
Aging / physiology
Diabetes Mellitus / physiopathology
Female
Heart Failure / etiology,  physiopathology*,  therapy*
Heart Rate / physiology
Humans
Male
Middle Aged
Monitoring, Ambulatory / instrumentation*
Motor Activity / physiology*
Pacemaker, Artificial*
Prospective Studies
Stroke Volume / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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