Document Detail

Activity of N-acetyltransferase in patients with malignant lymphomas.
MedLine Citation:
PMID:  692806     Owner:  NLM     Status:  MEDLINE    
Activity levels of N-acetyltransferase and acetylation types in patients with malignant lymphomas, following sulfadimidine loading, were established. The ratio of "fast" and "slow" acetylators among patients with malignant lymphomas is shown to be similar to that in control group. The rate of acetylation in "slow"-acetylating patients, however, was higher than in healthy controls. A relationship of N-acetyltransferase activity, tumor progression and, to a considerable extent, effectiveness of therapy was shown.
Chekharina YeA; L N Bulovskaya; M V Pavlova; R G Krupkin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neoplasma     Volume:  25     ISSN:  0028-2685     ISO Abbreviation:  Neoplasma     Publication Date:  1978  
Date Detail:
Created Date:  1978-12-02     Completed Date:  1978-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0377266     Medline TA:  Neoplasma     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  471-5     Citation Subset:  IM    
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MeSH Terms
Acetyltransferases / metabolism*
Lymphoma / enzymology*,  therapy
Remission, Spontaneous
Reg. No./Substance:
EC 2.3.1.-/Acetyltransferases

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