Document Detail


Activities of trypsin and lipase in duodenal aspirates of healthy preterm infants: effects of gestational and postnatal age.
MedLine Citation:
PMID:  7647149     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Lipase and trypsin activities were estimated in preprandially aspirated duodenal juice of preterm infants with gestational ages between 29 and 32 weeks (group I, n = 33) or between 33 and 36 weeks (group II, n = 22) during the first 6 weeks of postnatal life. The results were compared with the enzyme activities measured in 2- to 6-year-old children. There were no significant differences of the mean lipase or trypsin activities between the two groups lipase; group I 13.7 +/- 7.9, group II 15.9 +/- 9.8 U/ml; trypsin: group I 7.9 +/- 4.7, group II 8.5 +/- 5.1 U/ml). The activities of both enzymes increased significantly and similarly in both groups with postnatal age (lipase: group I r = 0.732, p < 0.01, group II r = 0.743, p < 0.01; trypsin: group I r = 0.705, p < 0.01, group II r = 0.669, p < 0.01). At the end of the study the lipase activities of both groups reached approximately 35% of the values found in the older children, whereas the trypsin activities reached the reference values within the 1st month of life. The results indicate an asynchronously age-related development of lipase and trypsin. The development of the lipase activity is delayed in comparison to the trypsin activity which should be considered in the nutritional management of preterm infants.
Authors:
G Boehm; U Bierbach; A DelSanto; G Moro; I Minoli
Related Documents :
6094459 - The influence of cefotaxime on intestinal flora and bleeding diathesis in infants and n...
18046559 - Intracranial hemorrhages due to late-type vitamin k deficiency bleeding.
8906139 - A randomized, controlled evaluation of two commercially available human breast milk for...
6605019 - Vitamin d nutritional status of premature infants supplemented with 500 iu vitamin d2 p...
8135569 - Postnatal somatic and mental development after periconceptional multivitamin supplement...
18595969 - Newborn vitamin a supplementation reduced infant mortality in rural bangladesh.
1611609 - Cerebral blood flow and oxygen metabolism in infants with hydrocephalus.
3977359 - Neonatal lupus erythematosus. a report of three cases associated with anti-ro/ssa antib...
9448579 - Mortality from hereditary cerebral haemorrhage with amyloidosis--dutch type. the impact...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biology of the neonate     Volume:  67     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1995  
Date Detail:
Created Date:  1995-09-28     Completed Date:  1995-09-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  248-53     Citation Subset:  IM    
Affiliation:
Center for Infant Nutrition to Prevent Illnesses in Adult Life, Milan, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aging*
Child
Child, Preschool
Duodenum / enzymology*
Gestational Age*
Humans
Infant
Infant, Newborn
Infant, Premature*
Lipase / metabolism*
Prospective Studies
Reference Values
Trypsin / metabolism*
Weight Gain
Chemical
Reg. No./Substance:
EC 3.1.1.3/Lipase; EC 3.4.21.4/Trypsin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Scanning gel densitometry of amniotic fluid acetylcholinesterase and butyrylcholinesterase: quantifi...
Next Document:  Intestinal transport and processing of immunoglobulin G in the neonatal and adult rat.